The 1. 2 Best Games For The Nintendo Switch. You just bought a new Nintendo Switch. First of all, good job! They’re still kind of hard to find. Now it’s time to figure out what games you want to play.

We’ve got you covered. The Switch’s library has been growing all year. Nintendo has managed to maintain a solid ratio of good games on their system, and at this point there’s a healthy selection of fantastic Switch games to choose from. The Nintendo Switch is a fascinating new game console built around a novel and well- executed…Read more Read.

Jaguar Land Rover Special Vehicle Operations is a quintessential niche product development group, a toy shop creating performance vehicles for true car lovers, and. BibMe Free Bibliography & Citation Maker - MLA, APA, Chicago, Harvard.

As with all of our Bests lists, we’ll be updating this one over the months and years to come. Each game we add in the future will need to replace an existing entry. Expect the list to continue to expand and improve over the months to come. Here are the 1. 2 best games you can get for the Nintendo Switch.

E! Online - Your source for entertainment news, celebrities, celeb news, and celebrity gossip. Check out the hottest fashion, photos, movies and TV shows! We can’t help it: sometimes we just hate certain cars. It could be because of the way they look, drive or how they were made. This can happen despite the badge it. Watch Dogs 2 got its final patch today, which makes impossible to use mods while online if you’re playing on PC. The game’s publisher, Ubisoft, says that this is. A young father is fighting for his life after he was found unconscious in the street with a bleed on the brain during his stag do in Magaluf. Alex Green, a. The story in the New York Times this week was unsettling: The New America Foundation, a major think tank, was getting rid of one of its teams of scholars, the Open. The latest news articles from Billboard Magazine, including reviews, business, pop, hip-hop, rock, dance, country and more.

The Legend of Zelda: Breath of the Wild is a monumental artistic achievement, a video game so creative and full of surprises that we’ll be talking about it for years to come. It’s also unlike any Zelda game before it. For years, Zelda games were defined by “no.” You can’t reach this place until later; you can’t solve this puzzle until you get the right item. Breath of the Wild is the best Zelda game to date, and it accomplishes that simply by saying yes. A Good Match For: Anyone who likes games that let you explore and make your own fun; horse lovers.

Not A Good Match For: Anyone who preferred the strict structure of other recent Zelda games. Read our review. Study our tips for the game. Watch it in action. Purchase From: Amazon Walmart Best Buy Gamestop.

Nintendo Switch: The Kotaku Review. The Nintendo Switch is a fascinating new game console built around a novel and well-executed Read more Read. 'Dance Moms' Cheryl Burke On Claims That Abby Lee Miller Is Talking Trash About Her In Prison; Tom Petty Honored By Jason Aldean & Keith Urban At 2017 CMT Artists Of.

Stardew Valley is an already- great game made indispensable by the Switch. The 2. 01. 6 farming/dating/life sim lets you forget your worries and embrace a soothingly banal life in the countryside. You water your crops in the morning, and think about how you’re going to improve your farm. You head in to town and stop by the general store to get seeds and chat up the cute boy you’ve had your eye on. And if you want, you explore the mysterious mine, gather magical materials, and uncover the deeper secrets of the valley. It’s a game with a seemingly endless amount to do, and it fits perfectly onto a handheld.

A Good Match For: Fans of games like Animal Crossing, Harvest Moon, or Minecraft. Anyone looking for a relaxing but terrifyingly addictive game. Not A Good Match For: Anyone looking for a straightforward game. Stardew Valley is calming and low- key, but it’s also extremely complex and doesn’t alway explain itself that well. Read our impressions of the Switch version. Study our tips for playing the game.

Watch it in action. Purchase From: Available digitally on the Nintendo e. Shop. Look, we weren’t expecting much from Mario + Rabbids: Kingdom Battle either. We were right there laughing along with the rest of the internet when we first saw those leaked promotional images of Ubisoft’s annoying Rabbid mascots dressed up as iconic Mario characters. But then Ubisoft showed the game itself, and… wait, a Mario- inspired take on XCOM tactics? One that looks like a first- party Nintendo game thanks to Nintendo’s developers lending a hand with production?

As it turned out, yep, Mario + Rabbids is a fantastic game. It’s a smart, streamlined take on the XCOM style of turn- based, positional tactics. It’s beautiful looking, and has an excellent musical score. And it’s just really goofy and fun. Each fight is an unpredictable scrum between team Mario and a bunch of chittering, idiot Rabbids, and the constantly escalating challenge will force you to think on your toes. And its digestible, 5- 1.

Switch. A Good Match For: Anyone waiting for a good Switch strategy game, XCOM fans, people who think they might like XCOM but are put off by how complicated it seems. Not A Good Match For: Anyone who just can’t stand Ubisoft’s Rabbids. The game is actually a lot more charming than the corny, Minions- like mascots on the cover might suggest, but if you really hate ‘em, you really hate ‘em. Read our review. Watch it in action. Purchase From: Amazon Walmart Best Buy Gamestop.

The makers of Thumper bill it as a “rhythm violence game,” which is a cheeky description but also an accurate one. The setup is simple: You control a glowing beetle as it zooms along a track through some sort of neon Hell dimension. In your path are glowing gems and various obstacles. You press buttons in time with the grinding, undulating music to get past those obstacles without blowing up. The music is relentless.

The beats are ferocious. The pace is unstoppable. Thumper takes a classic formula and strips it down to its rawest, most hypnotic base elements. The result is one of the finest rhythm games in years. A Good Match For: People who like rhythm games, people who like difficult rhythm games.

Not A Good Match For: Those who don’t want to play Switch games with headphones, those who get easily frustrated. Read our impressions of the PC version. Watch it in action. Purchase From: Available digitally on the Nintendo e.

Shop. Why have one good thing when you can have two? Good question. In the case of Puyo Puyo Tetris, those two good things are.. Tetris and Puyo Puyo, a pair of place- the- dropping- shapes games that are equally beloved, if not equally well- known, all around the world. In single- player, online or splitscreen multiplayer, you and up to three friends can compete in hectic matches that flip and flop from Tetris to Puyo Puyo and back again.

It’s a chaotic good time. A Good Match For: Fans of Tetris and fans of Puyo Puyo, obviously. Also, anyone looking for a fun competitive puzzle game to play with friends. Not A Good Match For: Those looking for a fleshed- out singleplayer game, anyone who prefers to solve puzzles without a time limitation.

Read our impressions of the game. Watch it in action. Purchase From: Amazon Walmart Best Buy Gamestop. Steam. World Dig 2 takes the backtracking, exploration and gradual upgrades of a Metroid game and combines them with the strategic spelunking of Dig Dug. The result is a charming, engrossing side- scroller loaded with smart ideas and clever challenges. That’s.. pretty much all we need to say about it. It’s a straightforward gaming pleasure.

A Good Match For: Fans of sidescrollers, Metroid- inspired games, and digging. Not A Good Match For: Anyone who hates platforming.

Steam. World Dig 2 isn’t as hard as some other similar games, but it does have some tricky challenges. Read our impressions of the Switch version.

Watch it in action. Purchase From: Available digitally on the Nintendo e. Shop. Something is wrong with Isaac’s mom: She thinks that she can hear God. And God, disturbingly enough, has instructed her to kill Isaac. The only way Isaac can get out of that hellish situation is by jumping into his basement—which happens to be endless, and full of terrors.

Thankfully, these demons can be defeated by directing Isaac’s tears, twin- stick shooter style, across Zelda- like dungeons. Well.. if Zelda dungeons were full of horrifying hellspawn, poop, and tons of mysterious items that you don’t know how to use. The Binding of Isaac has gotten several iterations over the years, and Afterbirth+ is the biggest expansion yet. A Good Match For: Players who like a challenge, especially of the roguelike variety. A lot of the appeal with the Binding of Isaac is how constantly it will surprise you with challenges you’ve never encountered before.

Not A Good Match For: Players who are sensitive to gross stuff or jokes about religion, or people who are just looking to relax while playing a game. Watch it in action. Purchase From: Amazon Walmart Best Buy Gamestop. Ah, the blue shell. There may be no better metaphor for the bleakness of life. One minute you’re cruising along, on top of the world, and then… BAM, you’re totally hosed.

Just when you thought you had it in the bag, life throws a blue shell. Mario Kart 8 isn’t really all that philosophical, of course.

NOVA - Official Website Cancer Warrior. Cancer Warrior. PBS Airdate: February 2. NARRATOR: Deep in this freezer is a drug of incalculable value. Years in development and millions of dollars spent on research, it is now being tested in human patients. It's an experimental cancer drug called "Endostatin," and if it works, it could profoundly change the way we treat cancer. John Matt is one of the chosen few selected to test Endostatin at the University of Wisconsin Comprehensive Cancer Center. He is part of what some have called the most anticipated clinical trial in medical history.

John gets 1. 2 vials of Endostatin every day. Unlike other cancer drugs, it's not a poison.

So far, it's had fewer side effects than aspirin. Watch Looking For Richard Dailymotion. Endostatin attacks cancer in a way that is so new, so radical, that most experts laughed at the idea when it was first proposed by Dr. Judah Folkman. Forty years ago he stumbled upon a clue—a hidden secret about how cancer really works. It would become his lifelong quest, to understand this relentless killer and find a better treatment for cancer patients. JUDAH FOLKMAN (Children's Hospital/Harvard Medical School): Patients going through these trials are in a desperate situation. Nothing else has worked and there's little time left and they have a fast clock running.

We all have a clock but theirs is very fast. And so they're very scared. JOHN MATT (Endostatin trial participant): I know.. I think my tumor is still growing slightly right now.

NARRATOR: John Matt has very advanced cancer. He has failed every other therapy he's tried. Endostatin may be his last, best hope. But will it work? NARRATOR: Seven days a week John Matt drives three hours back and forth to the hospital to get his Endostatin infusion. Fighting cancer has become his full- time job and it's the toughest battle of his life.

JOHN MATT: I know I could die. I should have died a few years ago. So I already know that I'm living on, as they say, "borrowed time." I want it to work.

And we're putting everything we can into making it work. NARRATOR: John is the sixteenth patient in Wisconsin to receive Endostatin. There are many more hoping to be number 1. DUANE GAY (Reporter and Endostatin Trial Participant): Kathy and Jerry, this is more than just a story.. NARRATOR: Duane Gay is a well- known reporter in Milwaukee, Wisconsin. DUANE GAY: It's really the inside story of two family farmers.

NARRATOR: In August of 1. Duane had just received the worst news of his life. DUANE GAY: I was told, "Not only is there extensive cancer in your lungs, numerous tumors, but we've found a large tumor in your liver." Here we were just married one year and planning a long life together and now we're being told that I probably won't be around in six months.

NARRATOR: Duane and his wife Teri stopped building the house they had dreamed about for a decade and started on a long, difficult medical odyssey. He had extensive surgery followed by months of chemotherapy. DUANE GAY: Chemotherapy is a hard thing to partner with because it's a poison. And you walk into the hospital to get your chemotherapy feeling a little bit okay, and you leave feeling worse. NARRATOR: Duane and Teri prayed every morning but the news just got worse. His cancer was still growing and there was nothing more his doctors could do.

Eighty miles away, in Madison, Wisconsin, Jim Thomas was inundated with patients trying to get into the Endostatin clinical trial. JAMES P. THOMAS (University Of Wisconsin Cancer Center): Over 4. The total number of patients is probably going to be in the low twenties, as far as how many patients will actually receive Endostatin here.

This is Mr. Gay. He's a 4. NARRATOR: This is how the most important decision in Duane Gay's life will be made.

His chances of getting into this study are slim. He has to have the right kind of tumors in places where they can be monitored and easily biopsied. FRED LEE : Probably the best one would be to biopsy this lesion here. There's some very accessible tumor. JAMES P. THOMAS: This gentleman is certainly an excellent candidate, so I think we'll approach him and ask him about entering into the study. FRED LEE:Sounds great. DUANE GAY: You have a good connection.

NARRATOR: In June of 2. Duane Gay received his first infusion of Endostatin. From now on, he has to come to the hospital seven days a week. It's a full time commitment. DUANE GAY: For the next couple of months this is my job. And it's a six and a half, seven- hour day on the easy days. But I think it's a small price to pay when you think about it.

I've worked a lot harder at things for less. NARRATOR: This is a Phase One clinical trial and the dose starts out very low. The doctors are mainly looking for side effects, but the patients want Endostatin to stop or shrink their cancer.

JAMES P. THOMAS: Patients that are going into phase one trials, they really are heroic in many aspects. We really can't advise them about whether something might make them very sick. We have no idea whether it's going to be effective or not. DUANE GAY:That's good, thanks.

I don't want to sound over- dramatic about it, but I'll tell you the way I look at it. It's a war, and this is an enemy that has stolen too many lives and rained misery onto too many families. But I feel honored and humbled to be a soldier and hit that beach. And that's honestly the way that I feel about it right now. NARRATOR: This is Children's Hospital in Boston, an important battlefield in the war against cancer, and where Endostatin was discovered in the laboratory of Dr. Judah Folkman. It was a hard won discovery—4. C. EVERETT KOOP (Children's Hospital of Philadelphia 1.

United States Surgeon General 1. When the history of medicine is written, it will be a story of a tremendous impact that was, at the beginning, pooh- poohed by his colleagues, at the end, proven to be what he said it would be and to have real, honest- to- goodness, practical value in the lives of patients, which is what Judah started out to do.

NARRATOR: Today, treating cancer often involves extreme measures and some of the most poisonous substances known. DON INGBER (Children's Hospital/Harvard Medical School): Conventional cancer drugs, most of which are still derivatives of, basically, the mustard gases used in warfare in World War I and are really toxic to any cell, have the known side effects of you losing your hair, losing your immune response, affecting your intestinal tract. NARRATOR: Another problem with chemotherapy is drug resistance, which occurs when cancer cells mutate and become resistant to drugs that once worked on them. But Endostatin doesn't attack the cancer cells at all. It goes after normal cells, the ones that feed the tumor and allow it to grow. Starving cancer by cutting off its food supply was Dr. Folkman's revolutionary idea, which arose almost by accident more than 4.

In 1. 96. 1 the U. S. Navy introduced the nuclear- powered aircraft carrier.

It was designed to stay at sea for months at a time. But there was a problem.

The blood supply could only be stored for about three weeks. To help find a long- lasting substitute for whole blood the Navy drafted young doctors, among them a surgeon named Judah Folkman. JUDAH FOLKMAN: I was assigned to work on the problem of, "could you dry the hemoglobin part of blood, the red part, like you dry coffee, and then reconstitute it by adding salt water and have it all ready to go?"NARRATOR: Dr. Folkman's job was to find out if reconstituted hemoglobin could keep tissue alive like real blood does.

With his colleague Fred Becker, Judah Folkman built a crude imitation of a circulatory system and attached a living organ, a rabbit thyroid. When the pump was turned on, the hemoglobin began to circulate and sure enough, the thyroid gland thrived. Then Dr. Folkman tried something that would turn this blood experiment into a four- decade quest to understand cancer. To see if the hemoglobin solution could not only sustain an organ but support new growth, Dr.